Description
ULTANE LIQUID ANAESTHETIC, 250ML
Description
ULTANE LIQUID ANAESTHETIC, 250ML is a volatile liquid anesthetic used for inhalation. It does not burn or explode and administers through vaporization. This halogenated anesthetic commonly provides general anesthesia.
Clinical Pharmacology
ULTANE LIQUID ANAESTHETIC, 250ML acts as an inhalational anesthetic to start and maintain general anesthesia. For a 40-year-old adult, the minimum alveolar concentration (MAC) of sevoflurane in oxygen ensures safe usage during anesthesia.
Clinical Studies
Researchers have administered sevoflurane to 3,185 patients in various clinical studies. Table 5 details the types of patients involved in these studies.
Indications and Usage
ULTANE LIQUID ANAESTHETIC, 250ML approves for both the induction and maintenance of general anesthesia in adults and children during inpatient and outpatient surgeries. Only healthcare professionals trained in anesthesia administration should use ULTANE.
Contraindications
Do not use ULTANE LIQUID ANAESTHETIC, 250ML in patients with a known or suspected genetic risk of malignant hyperthermia or sensitivity to sevoflurane. Refer to the Warnings section for more details.
Warnings
Risk of Renal Injury: Clinical and animal studies at low flow rates show a potential risk of renal injury. Exercise caution when administering sevoflurane.
Precautions
During anesthesia maintenance, increasing sevoflurane concentration may cause dose-related drops in blood pressure. Due to its low solubility in blood, sevoflurane can lead to rapid changes in hemodynamics.
Adverse Reactions
Clinical trials conducted in the United States, Canada, and Europe recorded adverse reactions. The trials compared sevoflurane to reference anesthetics such as isoflurane and enflurane.
Overdosage
If an overdose occurs, immediately stop sevoflurane, ensure the patient has an open airway, and provide assisted ventilation if necessary.
Dosage and Administration
Determine the concentration of sevoflurane from the vaporizer, ideally using a vaporizer calibrated for sevoflurane. Personalize the dosage based on the patient’s response to anesthesia.
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