Description
PHENOXYBENZAMINE(FENOXENE) 10MG CAPS 50`S
Fenoxene 10mg Capsule: High Blood Pressure Treatment for Pheochromocytoma
Fenoxene 10mg Capsule is prescribed to manage high blood pressure linked to pheochromocytoma, a tumor of the adrenal glands. By lowering blood pressure, it helps prevent heart attacks and strokes.
Mechanism of Action: Phenoxybenzamine
Phenoxybenzamine, the active ingredient in Fenoxene, works by blocking non-selective alpha-adrenergic receptors. This inhibits neurotransmitters like norepinephrine from acting on smooth muscle cells in blood vessels, causing vasodilation, reduced vascular resistance, and lower blood pressure.
Uses of Phenoxybenzamine
- Pheochromocytoma Management: Controls high blood pressure caused by this tumor.
- Preoperative Stabilization: Used to stabilize blood pressure before tumor removal surgery.
Administration and Dosage
Phenoxybenzamine is administered orally in capsule form. It should be taken with water, following specific dosage instructions provided by a healthcare professional based on individual needs.
Warnings, Precautions, and Side Effects
Warnings:
- Can cause dizziness and hypotension (low blood pressure).
- May lead to orthostatic hypotension (sudden blood pressure drop upon standing).
- Risk of fluid retention, which can worsen heart failure symptoms.
Precautions:
- Avoid activities requiring alertness until you know how the medication affects you.
- Rise slowly from lying or sitting positions to prevent dizziness.
- Consult a healthcare provider if you have a history of heart failure.
- Monitor for fluid retention signs, such as swelling and significant weight gain.
Side Effects:
- Common: Dizziness, weakness, nausea, nasal congestion, headache, palpitations.
- Serious: Severe hypotension, tachycardia (rapid heart rate), orthostatic hypotension, fluid retention.
Word of Advice
- Inform your healthcare provider about your full medical history, including heart, liver, kidney, lung conditions, and low blood pressure history.
- Regularly monitor your blood pressure as directed.
- Be cautious when changing positions to avoid dizziness and sudden drops in blood pressure.
- Watch for fluid retention signs and inform your doctor of any unusual changes.
- If scheduled for surgery, including dental procedures, inform your healthcare provider.
- Discuss dietary recommendations with your healthcare provider, especially concerning salt intake.
- Be alert for signs of allergic reactions, such as rash, itching, swelling, or difficulty breathing.
